Fz7-21, 1mg
£130.60
Delivery: 2 weeks
SKU
CLP0605-1mg
Fz7-21 (LPSDDLEFWCHVMY-NH2) TFA , a peptide antagonist of Frizzled 7 (FZD 7) receptors, selectively binds to FZD7 CRD subclass. The EC50 values are 58 and 34 nM for human and mouse FZD7 CRD, respectively. Fz7-21 impairs Wnt/β-catenin signaling in HEK293 cells stimulated with exogenous WNT3A (IC50=100?nM) or transfected with a construct expressing WNT3A or WNT1. Fz7-21 also blocks WNT3A-mediated stabilization of β-catenin in mouse L cells (IC50=50?nM).
Fz7-21 (LPSDDLEFWCHVMY-NH2) TFA , a peptide antagonist of Frizzled 7 (FZD 7) receptors, selectively binds to FZD7 CRD subclass. The EC50 values are 58 and 34 nM for human and mouse FZD7 CRD, respectively. Fz7-21 impairs Wnt/β-catenin signaling in HEK293 cells stimulated with exogenous WNT3A (IC50=100?nM) or transfected with a construct expressing WNT3A or WNT1. Fz7-21 also blocks WNT3A-mediated stabilization of β-catenin in mouse L cells (IC50=50?nM).
- Size: 1mg
- Purity: ≥95%
- CAS Number: No.2247635-23-8
- Molecular Formula: C83H114O23N18S2
- Molecular Weight: 1796.03
- Physical State: Lyophilized powder
- Storage: Store at -20℃.(Avoid freeze/thaw cycles)
- Brand: Saint Michael
- Catalogue No.: CLP0605-1mg
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.
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