FzM1.8 is an allosteric agonist of FZD4 that promotes TCF/LEF transcriptional activity in the absence of any WNT ligand, binds to FZD4 and activates the WNT/ beta-catenin pathway. FzM1.8 binds to stabilize FZD4, increases affinity to heterotrimer G proteins, and stimulates the release of the Gβγ subunit, which in turn activates PI3K.
- Size: 1mg
- Purity: ≥98%
- Brand: Saint Michael
- Catalogue No.: IF4320-1mg
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.
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