Gamma-Fibrinogen (377-395), 1mg
£168.69
Delivery: 2 weeks
SKU
CLP0610-1mg
This fibrinogen-derived inhibitory peptide attenuates microglia activation and suppresses relapsing paralysis in multiple sclerosis (MS). Fibrinogen is a regulator of microglia activation and interaction of fibrinogen with the microglia integrin receptor M1. Because blocking fibrinogen-M1 interactions affects the pro-inflammatory but not the pro-coagulant properties of fibrinogen, targeting this gamma-fibrinogen epitope could represent a potential therapeutic strategy for MS and other neuroinfla
This fibrinogen-derived inhibitory peptide attenuates microglia activation and suppresses relapsing paralysis in multiple sclerosis (MS). Fibrinogen is a regulator of microglia activation and interaction of fibrinogen with the microglia integrin receptor M1. Because blocking fibrinogen-M1 interactions affects the pro-inflammatory but not the pro-coagulant properties of fibrinogen, targeting this gamma-fibrinogen epitope could represent a potential therapeutic strategy for MS and other neuroinflammatory diseases associated with blood-brain barrier disruption and microglia activation.
- Size: 1mg
- Purity: ≥95%
- CAS Number: No.957792-67-5
- Molecular Formula: C100H165N25O28S2
- Molecular Weight: 2229.68
- Physical State: Lyophilized powder
- Storage: Store at -20℃.(Avoid freeze/thaw cycles)
- Brand: Saint Michael
- Catalogue No.: CLP0610-1mg
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.
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