GHRP amide, 5mg
The central E region of fibrin contains two sets of polymerization knobs, A and B, that are cryptic in fibrinogen but become exposed after thrombin cleavage of fibrinopeptide A (FpA) and fibrinopeptide B (FpB) from the N-terminus of the Aα-and Bβ-chains, respectively. The location of the binding holes and possible models for knob-hole interactions are known from X-ray crystallographic studies using synthetic peptide analogs of knobs A and B. When fibrinogen fragment D and double-D are crystallized in the presence of both peptide analogs, the knob A peptide mimic H-Gly-Pro-Arg-Pro-NH2 (GPRP-amide) forms H-bond interactions with residues γ364Asp, γ330Asp, γ329Gln, and γ340His found in hole a. In the same manner, the knob B peptide mimic H-Gly-His-Arg-Pro-NH2 (GHRP-amide) interacts with residues Bβ397Glu, Bβ398Asp, and Bβ432Asp in hole b.
- Size: 5mg
- Purity: ≥95%
- CAS Number: No.209623-54-1
- Molecular Formula: C19H32N10O4
- Molecular Weight: 464.53
- Physical State: Lyophilized powder
- Storage: Store at -20℃.(Avoid freeze/thaw cycles)
- Brand: Saint Michael
- Catalogue No.: CLP1003-5mg
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.