Human Granzyme A ELISA Kit, 48T
Granzyme A is a member of the granzyme family of the serine proteases found specifically in the cytotoxic granules of cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. Granzyme A is the most abundant protease in CTL and NK cells. It induces caspase-independent cell death when introduced into target cells by perforin. Human granzyme A is synthesized as a precursor (262 residues) with a signal peptide (residues 1-26), a propeptide (residues 27-28) and a mature chain (residues 29-262). The purified recombinant human Granzyme A consists of residues 26 to 262. After being activated by lysyl endopeptidase, it cleaves a thioester substrate.
- Size: 48T
- Storage: Store at 2-8℃
- Application: ELISA
- Brand: Saint Michael
- Catalogue No.: SEKH-0195-48T
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.