Insulin B (9-23), 5mg
£337.39
Delivery: 2 weeks
SKU
CLP0295-5mg
This insulin B-chain peptide binds to a class II histocompatibility complex (MHC) allele called I-Ag7. A number of autoimmune diseases has been linked to class II proteins encoded by the MHC. Type 1 diabetes, or insulin-dependent diabetes mellitus, is a T cell-mediated disease that results in autoimmune destruction of pancreatic β cells leading to hyperglycemia. This insulin B peptide may be a self-antigen candidate that could initiate the disease. Immunization with this peptide in mice led to a
This insulin B-chain peptide binds to a class II histocompatibility complex (MHC) allele called I-Ag7. A number of autoimmune diseases has been linked to class II proteins encoded by the MHC. Type 1 diabetes, or insulin-dependent diabetes mellitus, is a T cell-mediated disease that results in autoimmune destruction of pancreatic β cells leading to hyperglycemia. This insulin B peptide may be a self-antigen candidate that could initiate the disease. Immunization with this peptide in mice led to autoantibodies and insulitis.
- Size: 5mg
- Purity: ≥95%
- Molecular Formula: C72H116N20O22S1
- Molecular Weight: 1645.89
- Physical State: Lyophilized powder
- Storage: Store at -20℃.(Avoid freeze/thaw cycles)
- Brand: Saint Michael
- Catalogue No.: CLP0295-5mg
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.
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