Mouse Pentraxin 3/TSG-14 ELISA Kit, 48T
Pentraxin 3 (PTX3), also known as TNF-stimulated gene 14 (TSG-14), is a secreted glycoprotein belonging to the Pentraxin family of proteins. It is the prototypical long Pentraxin, exhibiting a C-terminal Pentraxin domain characteristic of the family, and a unique N-terminal domain. It is produced by several cell types including endothelial and mononuclear cells. PTX3 acts as a pattern recognition receptor with non-redundant roles in the innate immune response to several microbial agents including the fungal pathogen Aspergillus fumigatus. Overexpression leads to enhanced pro-inflammatory responses. PTX3 is induced in response to LPS and inflammatory cytokines including TNF-alpha and IL-1 beta.
- Size: 48T
- Storage: Store at 2-8℃
- Application: ELISA
- Brand: Saint Michael
- Catalogue No.: SEKM-0215-48T
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.