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Mouse Wnt-3a ELISA Kit, 96T

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£484.31
Delivery: 2 weeks
SKU
SEKM-0261-96T
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Wnt-3a is a secreted protein that is necessary for proper embryonic development of the hippocampus, anterior-posterior patterning, somite development, and tailbud formation. It also promotes self-renewal of hematopoietic stem cells, neural stem cells, and embryonic stem cells. The post-translational glycosylation and acylation of Wnts are essential for their efficient secretion and biological activity, respectively. Wnts bind to the cell surface Frizzled family receptors in conjunction with low-

Wnt-3a is a secreted protein that is necessary for proper embryonic development of the hippocampus, anterior-posterior patterning, somite development, and tailbud formation. It also promotes self-renewal of hematopoietic stem cells, neural stem cells, and embryonic stem cells. The post-translational glycosylation and acylation of Wnts are essential for their efficient secretion and biological activity, respectively. Wnts bind to the cell surface Frizzled family receptors in conjunction with low-density lipoprotein receptor-related protein family receptors (LRP5 or 6) resulting in the stabilization of intracellular beta-catenin levels. As intracellular beta-catenin levels rise, beta-catenin binds to TCF/LEF transcription factors leading to expression of Wnt target genes.

  • Size: 96T
  • Storage: Store at 2-8℃
  • Application: ELISA
  • Brand: Saint Michael
  • Catalogue No.: SEKM-0261-96T

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.

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