MPP+ iodide, a toxic metabolite of the neurotoxin MPTP, causes Parkinson's disease symptoms in animal models by selectively destroying dopaminergic neurons in the substantia nigra. MPP+ iodide is absorbed into dopaminergic neurons by dopamine transporters and exerts neurotoxic effects on mitochondria by influencing respiratory chain complex I. MPP+ iodide is also a high-affinity substrate for serotonin transporters (SERT).
- Size: 5mg
- Purity: ≥98%
- Molecular Formula: C 1 2 H 1 2 IN
- Molecular Weight: 297.14
- Physical State: Light yellow to yellow Solid
- Storage: Powder:2-8℃, 2 years;Insolvent(Mother Liquid):-20℃, 6 months;-80℃, 1 year
- Brand: Saint Michael
- Catalogue No.: IM6520-5mg
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.
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