Pannexin-1 (Panx1), Mimetic Blocking Peptide, 5mg

£235.81
Delivery: 2 weeks
SKU
CLP0305-5mg
This is a Pannexin-1 (Panx1) mimetic blocking peptide. Pannexin-1 is a recently identified membrane protein that can form gap junction-like connections allowing intercellular passage of Biochemical Products/Dyes when overexpressed in two adjacent oocytes or mammalian epithelial cell lines. Blockade of pannexin-1 in macrophage endogenously expressing the ATP-gated P2X7 receptor (P2X7R) blocks the initial dye uptake, but not the ionic current, and also blocks processing and release of interleukin-

This is a Pannexin-1 (Panx1) mimetic blocking peptide. Pannexin-1 is a recently identified membrane protein that can form gap junction-like connections allowing intercellular passage of Biochemical Products/Dyes when overexpressed in two adjacent oocytes or mammalian epithelial cell lines. Blockade of pannexin-1 in macrophage endogenously expressing the ATP-gated P2X7 receptor (P2X7R) blocks the initial dye uptake, but not the ionic current, and also blocks processing and release of interleukin-1 in response to P2X7R activation.

  • Size: 5mg
  • Purity: ≥95%
  • CAS Number: No.955091-53-9
  • Molecular Formula: C58H79N15O16
  • Molecular Weight: 1242.36
  • Physical State: Lyophilized powder
  • Storage: Store at -20℃.(Avoid freeze/thaw cycles)
  • Brand: Saint Michael
  • Catalogue No.: CLP0305-5mg

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.

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