PF-6274484 is a potent EGFR inhibitor with Kis of 0.14 nM and 0.18 nM for EGFR-L858R/T790M and WT EGFR, respectively. PF-6274484 inhibits EGFR-L858R/T790M autophosphorylation in H1975 tumor cells and EGFR WT in A549 tumor cells with IC50s of 6.6 and 5.8 nM, respectively[1].
- Size: 5mg
- Purity: ≥98%
- Molecular Formula: C 1 8 H 1 4 ClFN 4 O 2
- Molecular Weight: 372.8
- Physical State: Solid
- Storage: Powder:2-8℃, 2 years;Insolvent(Mother Liquid):-20℃, 6 months;-80℃, 1 year
- Brand: Saint Michael
- Catalogue No.: IP6760-5mg
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.
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