PKC Substrate [RRGR-pT-GRGRRGIFR], Phosphorylated, 5mg
£692.91
Delivery: 2 weeks
SKU
CLP1088-5mg
The native peptide, RRGRTGRGRRGIF, is proven to be a highly selective substrate for Protein Kinase C (PKC). It is based on the amino acid sequence 1487-1500 of the non-structural protein 3 of Hepatitis C virus (HCV). Substitution of Tyr1499 in HCV by Phe makes the peptide substrate more effectively phosphorylated by rat brain PKC (Km = 5μM) and mouse epidermal cell extracts (Km = 25 nM) than other kinases such as tyrosine kinases or other serine/threonine kinases. It is very useful for assaying
The native peptide, RRGRTGRGRRGIF, is proven to be a highly selective substrate for Protein Kinase C (PKC). It is based on the amino acid sequence 1487-1500 of the non-structural protein 3 of Hepatitis C virus (HCV). Substitution of Tyr1499 in HCV by Phe makes the peptide substrate more effectively phosphorylated by rat brain PKC (Km = 5μM) and mouse epidermal cell extracts (Km = 25 nM) than other kinases such as tyrosine kinases or other serine/threonine kinases. It is very useful for assaying PKC activity in the presence of other kinases in tissues and crude cell extracts.
- Size: 5mg
- Purity: ≥95%
- Molecular Formula: C69H126N35O19P1
- Molecular Weight: 1780.96
- Physical State: Lyophilized powder
- Storage: Store at -20℃.(Avoid freeze/thaw cycles)
- Brand: Saint Michael
- Catalogue No.: CLP1088-5mg
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.
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