β-Sheet Breaker Peptide iAβ5, 5mg

β-Sheet Breaker Peptide iAβ5 is a potent degrader of cerebral amyloid-beta (Abeta). Abeta deposition is associatied with the Alzheimer disease (AD), due to its related toxicity linked to its beta-sheet conformation and/or aggregation. β-Sheet Breaker Peptide iAβ5 reproducibly induces in vivo disassembly of fibrillar amyloid deposits. Thus, β-Sheet Breaker Peptide iAβ5 prevents and/or reverses neuronal shrinkage caused by Abeta, and reduces the extent of interleukin-1beta positive microglia-like cells that surround the Abeta deposits. β-Sheet Breaker Peptide iAβ5 reduces the size and/or number of cerebral amyloid plaques in AD. β-Sheet Breaker Peptide iAβ5 labeled by hydrophobic benzyl alcohol (HBA) tag, can be used for quantitative assay by showing vivid blue color under acidic conditions.

• Size: 5mg
• Purity: ≥95%
• CAS Number: No.182912-74-9
• Molecular Formula: C33H43N5O8
• Molecular Weight: 637.72
• Physical State: Lyophilized powder
• Storage: Store at -20℃.(Avoid freeze/thaw cycles)
• Brand: Saint Michael
• Catalogue No.: CLP1510-5mg

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.